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心跳過低(Bradycardia)

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What Is It?

Bradycardia is an abnormally slow heart rate of less than 60 beats per minute. A normal heartbeat is between 60 and 100 beats per minute.

Here's what happens during a normal heartbeat: The electrical signal that starts a heartbeat comes from the heart's sinus node, the natural pacemaker located in the upper portion of the right atrium. From the sinus node, the heartbeat signal travels to the atrioventricular (A-V) node, located between the atria, and then through the bundle of His (pronounced "hiss") -- a series of modified heart-muscle fibers located between the ventricles -- to the muscles of the ventricles. This triggers a contraction of the ventricles and produces a heartbeat.

Bradycardia, even as low as 50 beats per minute, can be normal in athletes and other people who are physically active. In these people, regular exercise improves the heart's ability to pump blood efficiently, so fewer heart contractions are required to supply the body's needs.

Bradycardia

In other cases, bradycardia can be a form of cardiac arrhythmia, a heart-rate abnormality. Cardiac arrhythmia can be caused by a problem in the sinus node, or it can be related to some disturbance in the passage of heartbeat signals through the A-V node and bundle of His. Bradycardia can occur with toxic levels of certain drugs, such as digoxin (Lanoxin) and narcotics. Also, bradycardia sometimes is a side effect of certain medications, including propranolol (Inderal), atenolol (Tenormin), metoprolol (Toprol-XL), sotalol (Betapace), verapamil (Calan, Isoptin, Verelan) and diltiazem (Cardizem, Dilacor-XR). Bradycardia also occurs in some people who have certain medical illnesses not related to the heart, such as:

  • An abnormally low level of thyroid hormones (hypothyroidism)

  • An abnormally low body temperature (hypothermia)

  • A very high blood potassium level

  • Lyme disease

  • Typhoid fever

Symptoms

Bradycardia can cause dizziness, weakness, lack of energy or fainting spells.

If bradycardia is caused by a medical illness, there will be additional symptoms that are specific to that illness. For example, people whose bradycardia is due to severe hypothyroidism also can have constipation, muscle cramps, weight gain (often despite poor appetite), very dry skin, hair that is thin and dry, an abnormal sensitivity to cold temperatures and other symptoms related to low levels of thyroid hormones.

Diagnosis

Your doctor will ask about your family history of heart disease, cardiac arrhythmias and fainting spells. He or she also will review your current symptoms and your personal medical history, including your use of medications that may cause bradycardia.

During the physical examination, your doctor will check your heart rate and rhythm, and your pulse. You may be asked to do some sit-ups or other exercise so that your doctor can see if your heart rate rises normally when your heart is asked to do more work. Your doctor also will check for physical signs of thyroid abnormalities, including an enlarged thyroid gland, very dry skin, and hair that is thin and dry.

To further evaluate your bradycardia, your doctor will order an electrocardiogram (EKG). However, because some forms of bradycardia come and go, a one-time office EKG may be normal. If this is the case, a test called ambulatory electrocardiography may be done. During this test, the patient wears a portable EKG machine called a Holter monitor, usually for 24 hours. If your symptoms are infrequent, you may wear a monitor for longer. You will be taught to press a button to record your EKG reading when your symptoms occur.

Depending on the results of your physical examination, other tests may be necessary to check for medical illnesses that produce bradycardia. For example, if you have symptoms and physical signs of hypothyroidism, your doctor may order blood tests to measure levels of thyroid hormones and TSH, a pituitary gland hormone that stimulates the thyroid. Your doctor also may order blood tests for cholesterol and certain liver enzymes, which often are elevated in people with hypothyroidism.

 

Expected Duration

How long bradycardia lasts depends on its cause. For example, normal bradycardia in a well-trained athlete will last as long as the athlete maintains his or her usual level of exercise. When bradycardia occurs as a side effect of medication, it usually will go away as soon as the drug that triggered the bradycardia is used by the body or excreted in the urine. Bradycardia caused by hypothyroidism will go away quickly after treatment with thyroid hormones. Certain forms of bradycardia resulting from cardiac arrhythmias can be cured with a permanent pacemaker.

Prevention

There are no general guidelines to prevent all forms of bradycardia. When bradycardia occurs as a side effect of medication, the problem can be prevented by either switching the drug or reducing its dose.

Treatment

In most cases, bradycardia in healthy, well-trained athletes does not need to be treated. In fact, in most people, bradycardia does not require treatment unless patients have symptoms that are clearly due to a slow heartbeat. The following are conditions that produce bradycardia that requires treatment:

  • Cardiac arrhythmias resulting from sinus node dysfunction. In people with frequent, severe symptoms of sinus-node dysfunction, the main treatment is usually a permanent pacemaker, an implanted device that generates electrical impulses to regulate the heartbeat.

  • Cardiac arrhythmias resulting from A-V node problems. In people with A-V node problems, the passage of heartbeat signals may be blocked to different degrees. Some patients with less severe degrees of A-V block do not need treatment. Others may simply be monitored with frequent EKGs, especially if they don't have any symptoms and have a heart rate that is adequate for their daily activities. People with the most severe form of A-V block (called third-degree A-V block) can be treated with a special dual-chambered permanent pacemaker, a pacemaker with one electrode in the atrium and one in the ventricle.

  • Hypothyroidism. Hypothyroidism is treated with replacement doses of thyroid hormones. Synthetic forms of these hormones are available -- levothyroxine (Synthroid, Levothroid and others), liothyronine (Cytomel, Triostat) or liotrix (Thyrolar) -- as well as thyroid extract.

  • Lyme disease. Treatment with antibiotics clears the infection and the bradycardia almost always resolves.

When To Call a Professional

Call your doctor if your pulse is less than 60 beats per minute. This is especially important if you have had dizziness, weakness, lack of energy or fainting spells.

Prognosis

In well-trained athletes with normal bradycardia, the slow heartbeat is often a sign of overall good health. In other people with bradycardia, the outlook depends on the underlying disorder. For example, the prognosis is usually good in people with hypothyroidism, since treatment with thyroid hormones can relieve bradycardia and other symptoms related to low hormone levels. In some elderly patients, hormone dosages may need to be increased very slowly over several weeks to prevent straining the heart. At one time, the prognosis for people with third-degree A-V block was poor, with 50% of patients dying within one year of diagnosis. Now, however, the availability of permanent pacemakers has improved the prognosis for many people with cardiac arrhythmias.

 

  • 一般文獻把心跳低於60(每分鐘)定義為心跳過低,但是通常心跳低
    於50才有不適症狀出現
  • 我們的自然心跳頻率(Natural Rhythm)由心竇 (Sinus Node,或稱
    為竇房結SA node)控制,一般人約為每分鐘100-120,但經過自律神
    經之交感(昇高)及副交感(降低)調控後心跳成為每分鐘約72下
  • 心跳過低的不適症狀包括疲勞,虛弱,炫暈,暈倒,胸悶,喘不過氣,強
    烈快速心跳,睡眠不佳或驚醒等
  • 心跳過低的常見原因之一為心竇自然頻率過低(遺傳或後天; Sick
    Sinus Syndrome),即使自律神經微調也補償不足; 另一常見原因為
    心竇之電訊堵塞(SA Node Block),由房室結(AV Node) 產生的訊號
    (頻率較低)反而成為心跳頻率. 此外,心肌缺氧,心閥缺陷,或隱型中
    風等都可能造成心跳過低
  • 如果年輕時心跳正常,老了以後才過低,則生理機能老化(包括心臟,
  • 許多運動員(尤其是馬拉松選手)常有心跳過低現象,有些是遺傳
    有些為後天(運動訓練)造成
  • 白天心跳正常,睡覺以後才過低(很多人並不自覺或半夜常因心悸驚
    醒),則可能是自律神經調解不當所致. 一般人白天交感主導(以提供
    所需能量),晚上副交感主導;但少數人白天心跳已不夠高(如60), 晚
    上若副交感再過度啟動,則會造成心跳過低(低於50)
  • 非心臟型心跳過低的生理原因還包括新陳代謝或內分泌不正常(尤
    其是甲狀腺);電解質不正常(鉀離子等);免疫系統不正常;食物中毒
    或服用毒品
  • 利用24小時Holter霍特機監控,發現心跳過低(BRadycardia)及低血
    壓,與心跳過速(Tachycardia)及高血壓,常伴隨發生且循環多次,這
    是因為心跳過低造成系統缺氧及低血壓,只好啟動交感(心跳過速)
    來彌補
  • 如果病患並沒有不舒服的癥兆,醫生通常都不予以治療
  • 有些醫生會開阿托品Atropine 給心跳過低的病患服用; 還有些醫生
    會開降血壓的藥,避免交感啟動時血壓或心跳過高; 藥物治療效果
    多半不太理想
  • 許多且有嚴重徵兆的病患,醫生會建議使用植入式心律調整器
    (Implanted Pace Maker)
  • 對許多輕度至中度心跳過低的患者而言,飲食及生活型態適度改善
    並持之有恆,即可有效克服不適徵兆
  • 少吃肥肉,低鹽,少喝酒,多吃蔬菜,魚,及Omega-3可以讓血管管壁減
    少積垢,並活絡自律神經
  • 有氧運動(會喘且會流汗的那種)可增強心肌,讓心臟打血有力;因此
    即使心跳低,血壓及氧氣供應量仍然充足
  • 醫生開藥前最好先測量病患的HRV(自律神經總活性)及交感/副交
    感平衡指標LF/HF, 以確認是否有副交感過盛的趨勢; 還可利用心
    律大師來評估或監控血管緊張度(即周邊血管阻力)
  • 服藥後若發現HRV持續下降, LF/HF遠偏離正常值(例如太低或太
    高),或體力大不如前,應與醫生研究改量或改藥
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