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50% Of Alzheimer's Cases Preventable With Lifestyle Changes
Public / Patient:3.7 10 ratings Health Professionals:4.3 3 ratings More than 50% of cases of Alzheimer's Disease could be prevented through lifestyle changes and reducing major risk factors like low education, smoking, lack of exercise, and treating and preventing chronic conditions like depression, diabetes and mid-life high blood pressure and obesity, say researchers from the University of California, San Francisco (UCSF).

The authors of the study were Dr Deborah Barnes, an associate professor of psychiatry at UCSF, and a mental health researcher at the San Francisco VA Medical Center, and Dr Kristine Yaffe, professor of psychiatry, neurology and epidemiology at UCSF. You can read how they analyzed data from studies around the world involving hundreds of thousands of participants and arrived at these findings in the 19 July early online issue of The Lancet Neurology.

There are currently about 33.9 million people worldwide with Alzheimer's Disease, with three times this number expected by 2050.

Barnes and Yaffe investigated the available evidence on seven potentially modifiable risk factors for Alzheimer's Disease. They projected how reduction in these factors might affect the prevalence of the disease by calculating the percentage of cases tied to a given factor, and the number of cases that might be prevented if each factor were reduced by 10% and 25%, both worldwide and in the US.

The seven modifiable risk factors that they investigated were: diabetes, high blood pressure in mid-life, obesity in mid-life, smoking, depression, low educational attainment or cognitive inactivity, and physical inactivity.