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Rate of↑Na should not exceed 10-12 mEq/L per day to avoid osmotic demyelination (central potine myelinolysis)

Central potine myelinolysis : spastic quadriplegia, dysarthria, and dysphagia)

 

The rapidity with which hypoNa is corrected should be tailored to the severity of symptoms:

l   Mild symptoms: 0.5 mEq/L per hour

l   Moderate symptoms: 1.0 mEq/L per hour

l   Severe symptoms: 1.5 mEq/L per hour