A. Refereed Papers - Review: 蕭振文，戴謙，楊惠郎。1997。以免疫去勢調控動物之生殖。科學農業。 45(5,6):176-185 .
- Review: 蕭振文，劉瑞珍，戴謙，楊惠郎，宋永義。1997。逢機複製多態性核甘酸在畜產之應用。科學農業45(9,10):275-283.
- 蕭振文，戴謙，宋永義，楊惠郎。1998。核酸疫苗研發之動物模式。科學農業 46:(5, 6): 209-216。
- 蕭振文，施勇綸，楊惠郎，戴謙，宋永義。1998。生長分化因子之生物功能。科學農業46(11,12)：366-375。
- 楊惠郎，蕭振文，戴謙，宋永義。1998。生物技術在畜產上之應用。畜產研究 31: (2) 197-210。
- M.Y.Liu, Y.L.Chang, J.Ma, H.L.Yang, M.W.Hsu, C.J.Chen, J.Y.Chen, C.S.Yang。1997。 Evaluation of multiple antibodies to EB us as markers for detecting patients with nasopharyngeal carcinoma J. of Medical Virology 52:262-269 .
- Review：Huey-Lang Yang。1999。The application of new biotechnology for disease prevention in animal pp. 73-82 in “ Biotechnology in agriculture in Asia, Asian productivity Organization.
- J.W.Shiau, T.K. Tang, Y.L. Shih, C.Tai, Y.Y.Sung, J.L.Huang, H.L.Yang.。2000。 Mice immunized with DNA encodes a modified Pseudomonas aeruginosa exotoxin A develops protective immunity against exotoxin intoxication . Vaccine Vol. 19, issue 9-10, 1106-1112(SCI) .
- J.P.R. Rajan, Carmen Lopez, John Han-You Lin, Huey-Lang Yang. 2001。Infection of Vibrio alginolyticus on cultured cobia, Rachycentron canadum in Taiwan. Bulletin of the European Association of Fish pathologist 21(6), 228-235(SCI)
- Carmen Lopez, J.P.R. Rajan, John Han-You Lin, Tsun-Yung Kuo & Huey-Lang Yang. 2002 Disease outbreak in seafarmed Cobia (Rachycentron canadum) associate with Vibrio spp., Photbacterium damselae ssp piscida, monogenean and mycosporean parasites Bulletin of the European Association of Fish pathologist 22(3), 206-211.
- Lopez C, J.P.R. Rajan, John Han-You Lin, Tsun-Yung Kuo & Huey-Lang Yang. (2002)Disease outbreak in seafarmed Cobia (Rachycentron canadum) associate with Vibrio spp., Photbacterium damselae ssp piscida, monogenean and mycosporean parasites Bulletin of the European Association of Fish pathologist 22 (3), 206-211.
- P.R. Rajan, John H-Y Lin, M-S. Ho and H-L. Yang, (2003) Simple and rapid detection of Photobacterium damselae subsp. piscida by a PCR technique and plating method Jour of Applied Microbiology ,(J. of Applied Microbiology 2003, 95, 1375-1380. (PDF download)
- H.S. Kuo, Y-L Su, H-L. Yang, and T.Y. Chen, (2005) Identification of Chinese medicinal fungus Cordyceps sinensis by PCR-single stranded conformation polymorphism and phylogenetic relationshipJ. Agri. Food Chem. (PDF download)
- Yang, H.-L., Chien-Chih Yu, and John Han-You Lin, ?Fish oral delivery system using Artemia encapsulated with recombinant E. coli. International Association for Biologicals.: Progress in fish vaccinology. (ed) Midlyng PJ, Dev. Biol. Basel, Kreger, 2005, Vol. 121, pp 175-180, 2005
- Han-Tso Lin, Han-You Lin, Huey-Lang Yang,( 2005) Studies of the Histology and Histochemical Enzyme-Staining Patterns of Major Immune Organs in Malabar Grouper (Epinephelus malabaricus, Bloch et Schneider), Journal of Fish Biology 66, 729-740. (PDF download)
- Chen SP, Yang HL, Her GM, Lin HY, Jeng MF, Wu JL, Hong JR. (2006) Betanodavirus induces phosphatidylserine exposure and loss of mitochondrial membrane potential in secondary necrotic cells, both of which are blocked by bongkrekic acid. Virology 347(2):379-91. (PDF download)
- Chen YM, Su YL, Lin JH, Yang HL, Chen TY. (2006)Cloning of an orange-spotted grouper (Epinephelus coioides) Mx cDNA and characterisation of its expression in response to nodavirus. Fish Shellfish Immunol 20(1):58-71. (PDF download)
- Chen SP, Yang HL, Lin HY, Chen MC, Wu JL, Hong JR. (2006)Enhanced viability of a nervous necrosis virus-infected stable cell line over-expressing a fusion product of the zfBcl-xL and green fluorescent protein genes. J Fish Dis 29(6):347-54. (PDF download)
- Kuo H-C, Su Y-L, Yang H-L., Huang I-C, and Chen T-Y*. Differentiation of Cordyceps sinensis by A PCR-Single-Stranded Conformation Polymorphism Based Method and Characterization of the Fermented Products in Taiwan. FOOD BIOTECHNOLOGY 2006;20:161-170.
- John Han-You Lin, Tzong-Yueh Chen, Ming-Shyan Chen, Huey-En Chen, Ray-Liang, Chou, Z. Y. Cheng, M. S. Su, and Yang, H.-L.* Vaccination with three inactivated pathogens of cobia (Rachycentron canadum) stimulates protective immunity AQUACULTURE 255, 2006:125-132
- Lin C.-C *, Lin J H-Y *, Chen M.-S and Yang, H.-L.*. An oral Nervous Necrosis Virus vaccine that induces protective immunity in larvae of grouper (Epinephelus coioides). AQUACULTURE 2007;268:265-273
- Ou M-C, Chen Y-M, Jeng M-F, Chu C-J, Yang, H.-L., and Chen T-Y*. Identification of Critical Residues in Nervous Necrosis Virus B2 for dsRNA-binding and RNAi-inhibiting Activity through by Bioinformatic Analysis and Mutagenesis. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2007;361:634-640
- Chen Y-M, Wei C-Y, Chien C-H, Chang H-W, Huang S-I, Yang, H.-L., and Chen T-Y*. 2007. Myostatin Gene Organization and Nodavirus-influenced Expression in Orange-spotted Grouper (Epinephelus coioides). Comp. Biochem. Physiol. D, Genomics Proteomics 2:215-227
- Lin H-T, Lin J H-Y, Lopez C, Chen Tzong-Yueh, Chen M-S, and Yang H-L. 2008. A Comparison of the Expression of immunity-related rag-1 and ikaros Genes with Histogenesis of the Thymus in Epinephelus malabaricus (Bloch & Schneider). Aquac. Res. 39:252-262. (PDF download)
- Chen Y-M, Su Y-L, Shie P-S, Lin J H-Y, Yang H-L, and Chen Tzong-Yueh. 2008. Grouper Mx Confers Resistance to Nodavirus and Interacts with Coat Protein. Dev. Comp. Immunol. 32:825-836. (PDF download)
- Kuo H-C, Su Y-L, Yang, H.-L., and Chen T-Y*. 2008. Establishment and Application of PCR-SSCP Profile for Molecular Typing of Cordyceps Fungi. Revised to Food Biotechnol. In press(SCI)
B. Conference papers a.國際會議 1. Keynote speaker: Development of disease prevention system for warm water fish aquaculture, 2004
International Conference of Marine science and technology, 13-14, 2004, Kao-Hsiung, Taiwan 2. Invited speaker. The development of an oral Nervous Necrosis virus vaccine and its efficacy test in grouper, International Biotech Conference & Exhibition (IBC&E) Nov. 25-27, 2004, Ka0-Hsing, Taiwan 3. Invited oral presentation: Fish oral vaccine with recombinant E. coli. encapsulated in brine shrimp induces protective immunity 2003, 3rd International Symposium of fish vaccinology. Bergen, Norway. 4. Invited oral presentation: The development of fish disease system December 1-4, 2003
International marine biotechnological science & industry conference at National Museum of Marine Biology and Aquarium, Taiwan 5. Invited speaker: The development of vaccination program for NNV infection in grouper, 2002
International symposium on agricultural biotechnology. 6. Han-Tso Lin, C. Lopez, H. Y. Lin and H-L. Yang. How soon the grouper can arm itself? International symposium on agricultural biotechnology, Dec. 13-14, 2002 Poster award 7. H.C. Kuo, H.L. Yang and T. Y. Chen, Phylogenetic analysis of the Chinese herb medicine Cordycepes sinensis based on 18 S rRNA gene. International symposium on agricultural biotechnology, Dec. 13-14, 2002 6. Invited speaker: Immuno-response to killed and recombinant subunit vaccines of Nervous necrosis Virus in groper. 2001
Taiwan-Norway-USA International Symposium on fish virus pathogenesis and disease control, 2001. Sept. 27-31 7.Invited speaker: Fish oral vaccine method combining bio-encapsulation and recombinant DNA technology,2001
Asian aquaculture forum Nov. 25-29, 2001 8. Invited speaker: The application of biotechnology for the development of fish viral vaccine, Taiwan-Japan conference in Biotechnology for Aquatic animals, April 2001, Tokyo Japan 9. Invited speaker: Fish oral vaccine method combining Bio-encapsulation and recombinant DNA technology. Taiwan-Norway-USA International Symposium on fish virus pathogenesis and disease control 2001. Sept. 27-31. 10 Invited speaker: Immuno-response to killed and recombinant subunit vaccines of Nervous necrosis Virus in groper. Taiwan-Norway-USA International Symposium on fish virus pathogenesis and disease control 2001. Sept. 27-31 11.H.L.Yang. (2001) The development of recombinant subunit vaccine for Nervous Necrosis Virus International Conference on fish disease: European Fish Pathologist Dublin, Sept. 7-12, 2001. 12.Vibrosis in cultured cobia, Rachycentron canadum, L in Taiwan, Asian aquaculture forum Nov. 25-29, 2001. 13.Invited speaker: Fish oral vaccine method combining bio-encapsulation and recombinant DNA technology, Asian aquaculture forum Nov. 25-29, 2001. 14.Immuno-response to killed vaccine and recombinant subunit vaccine of nervous necrosis Virus in grouper, Asian aquaculture forum Nov. 25-29, 2001. 15.Poster session: Cheng-Chieh Wang, John Han-You Lin, Chin-Chiu Lin, Tzong-Yueh Chen, and Yang H.-L. Cloning of rag-1 gene from cobia, Rachycentron canadum, and its expression during ontogenesis 2003, 3rd international Symposium of fish vaccinology 16.Poster session: John H.Y. Lin*, T. Y. Kuo+, H.C. Liang*, I.C. Huang#, and Yang H.-L.*,# The development and characterization of cell lines of grouper (Epinephelus coioides) and cobia (Rachycentron canadum) 2003, 3rd international Symposium of fish vaccinology 17.Lin S-C, Yang H.-L., and Chen Tzong-Yueh.? 2003.? Development of Nonspecific Binding Sequence and Non-cell Specificity for DNA Delivery System. Eleventh Symposium on Recent Advances in Cellular and Molecular Biology. Kenting, Taiwan, Abs. #P52 18.Chen Y-M, Yang H.-L., and Chen Tzong-Yueh.? 2003.? cDNA clonging of Myxovirus Resistance (Mx) Gene, an INF-inducible Antiviral Protein from the Grouper (Epinephelus coioides). The 2003 Annual Conference of the Fisheries Society of Taiwan. Kaohsiung, Taiwan, Abs. #B-3-1 19.Huang S-I, Lin S-C, Yang H.-L., and Chen Tzong-Yueh.? 2004.? Development of a Universal DNA Delivery System. Twelfth Symposium on Recent Advances in Cellular and Molecular Biology. Kenting, Taiwan, Abs. #P106 20.Chuang H-C, Chen Y-M, Yang H.-L., and Chen Tzong-Yueh.? 2004.? Study the Antimicrobial activity of Penaeidins. The 19th Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan, Abs. #P16. 21.Chen Y-M, Mao M-H, Su Y-L, Chuang H-C, Yang H.-L., Lin H-Y, and Chen Tzong-Yueh.? 2004.? Proteomic Approach Identifies Small Heat Shock Protein as a Potentially Biomarker to Monitor Nervous Necrosis Virus Infection. 2004 International Conference of Advanced Biotechnology-Dialogue between Proteomics and Biotechnology, Tainan, Taiwan, Abs. #P2. 22.Chen Y-M, Su Y-L, Yang H.-L., and Chen Tzong-Yueh.? 2004.? The Characterization and Expression of the Mx Protein in the Grouper Cell Line. The 2004 Annual Conference of the Fisheries Society of Taiwan, Taipei, Taiwan, Abs. #A-1-2. 23.Chen Y-M, Wei C-Y, Chang H-W, Yang H.-L., and Chen Tzong-Yueh.? 2004.? Cloning, Characterization and Application of the Grouper (Epinephelus coioides) Myostatin Gene. The 2004 Annual Conference of the Fisheries Society of Taiwan, Taipei, Taiwan, Abs. #A-5-6. 24.Chen Y-M, Mao M-H, Su Y-L, Chuang H-C, Yang H.-L., Lin H-Y, and Chen Tzong-Yueh.? 2004.? Proteomic Approach Identifies Small Heat Shock Protein as a Potentially Biomarker to Monitor Nervous Necrosis Virus Infection. The 2004 Annual Conference of the Fisheries Society of Taiwan, Taipei, Taiwan, Abs. #E-C5. 25.Lin H-Y, Chen Tzong-Yueh, Chen M-S, Chen H-E, Su Y-L, ChouT-I, Su M-S, and Yang H.-L. 2004. Development of a Multivalent Bacterial Vaccine for Vibrio alginolyticus, V. parahaemolyticus and Photobacterium damselae Subspecies piscicida and Its Evaluation in Cobia (Rachycentron canadum) . The 2004 Annual Conference of the Fisheries Society of Taiwan, Taipei, Taiwan, Abs. #E-32. 26. Keynote speaker: Development of disease prevention system for warm water fish aquaculture, 2004. 2004 International Conference of Marine science and technology, 13-14, 2004, Kaohsiung, Taiwan 27. Invited speaker: The development of an oral Nervous Necrosis virus vaccine and its efficacy test in grouper, International Biotech Conference & Exhibition (IBC&E) Nov. 25-27, 2004, Kaohsiung, Taiwan 28. Huang S-I, Yang H.-L., and Chen Tzong-Yueh. 2005. Development of a Universal Biological Materials Delivery System. The 20th Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan, Abs. #P38 29. Su Y-L, Chen Y-M, Yang H.-L., and Chen Tzong-Yueh. 2005. The Characterization and Expression of the Mx Protein in the Grouper Cell Line. Thirteenth Symposium on Recent Advances in Cellular and Molecular Biology. Kenting, Taiwan, Abs. #P111. 30. Chen Y-M, Wei C-Y, Chang H-W, Yang H.-L., and Chen Tzong-Yueh. 2005. Cloning of the Grouper (Epinephelus coioides) Myostatin Gene. The 2005 Annual Conference of the Fisheries Society of Taiwan, Taipei, Taiwan, Abs. #BO-12. 31. Chen Y-M, Su Y-L, Shie P-S, Yang H.-L., and Chen Tzong-Yueh. 2005. Resistance to Nodavirus Activity by Coat Protein Interaction with the Interferon-regulated GTP-binding Proteins, Grouper Mx. The 2005 Annual Conference of the Fisheries Society of Taiwan, Taipei, Taiwan, Abs. # BO-13. 32. Ou M-C, Chuang H-C, Chen Y-M, Lee G-B, Lee S-S, Yang H.-L., and Chen Tzong-Yueh. 2005. Development of Diagnostic methods for Nervous Necrosis Virus. The 2005 Annual Conference of the Fisheries Society of Taiwan, Taipei, Taiwan, Abs. # AP-6. 33. Chien C-H, Chen Y-M, Wei C-Y, Yang H.-L., and Chen Tzong-Yueh. 2005. Functional Analysis of the Grouper Myostatin Gene Promoter and the Application of Myostatin in Grouper. The 2005 Annual Conference of the Fisheries Society of Taiwan, Taipei, Taiwan, Abs. #BP-7. 34. Shie P-S, Chen Y-M, Su Y-L, Yang H.-L., and Chen Tzong-Yueh. 2005. The Characterization and Expression of the Mx Protein in the Grouper Cell Line. The 2005 Annual Conference of the Fisheries Society of Taiwan, Taipei, Taiwan, Abs. # BP-15. 35. Chen Y-M, Su Y-L, Shie P-S, Yang H.-L., and Chen Tzong-Yueh. 2006. Modulation of Nodavirus Coat Protein Localization by Binding to the Interferon-regulated GTP-binding Proteins, Grouper Mx. Fourteenth Symposium on Recent Advances in Cellular and Molecular Biology. Kenting, Taiwan, Abs. #P101. 36. Liu Y-R, Huang S-I, Yang H.-L., and Chen Tzong-Yueh. 2006. Characterization and Functional Analysis of a Delivery System Mediated by Protein Transduction Domain. The 21th Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan, Abs. #P649. 37. Chen Tzong-Yueh, Chen Y-M, and Yang H.-L.. 2006. Identification and Characterization of the Responsive Genes in Grouper for Nervous Necrosis Virus Infection. 2006 Symposium on Biotechnology Development in Taiwan: Biotechnology in Aquaculture, Tainan, Taiwan, Abs. #S10. 38. Chen Y-M, Su Y-L, Shie P-S, Yang H.-L., and Chen Tzong-Yueh. Inhibition of Nodavirus Activity by Binding Directly to the Mx Protein in Grouper (Epinephelus coioides) Cell. Aquaculture 2006, Florence, Italy, Abs 39.Ou M-C, Chuang H-C, Chen Y-M, Lee G-B, Lee S-S, Yang H.-L., and Chen Tzong-Yueh. 2006. Development of Fast and Sensitive Diagnostic Methods for Nneverous Necrosis Virus by Using Microfluidic Chip and Real-time PCR. Aquaculture 2006, Florence, Italy, Abs. 40. Chuang H-C, Chen Y-M, Lin H-Y, Yang, H.-L., and Chen T-Y*. 2006. Detection of Nerve Necrosis Virus by a Real-time PCR Method and Characterization of Its Tissue Distributions in Giant Grouper (Epinephelus lanceolatus). VNN 2006 First International Symposium on Viral Nervous Necrosis of Fish, Hiroshima, Japan, Abs.#PP-4. 41. Ou M-C, Chen Y-M, Jeng M-F, Yang, H.-L., and Chen T-Y*. 2006. Identification of Orange-spotted Grouper (Epinephelus coioides) Nervous Necrosis Virus (OGNNV) B2-Arg53 as a Critical Residue for dsRNA Binding Activity. VNN 2006 First International Symposium on Viral Nervous Necrosis of Fish, Hiroshima, Japan, Abs.#PP-7. 42. Chen Y-M, Su Y-L, Shie P-S, Yang, H.-L., and Chen T-Y*. 2006. Inhibition of Nodavirus Activity by Binding Directly to the Interferon-regulated GTP-binding Proteins, Grouper Mx. The 40th Annual Meeting of the Taiwan Society of Microbiology, Taipei, Taiwan, Abs. #V-4. 43. Chen Y-M, Su Y-L, Shie P-S, Yang, H.-L., and Chen T-Y*. 2006. Resistance to Nodavirus Activity by Coat Protein Interaction with the Interferon-regulated GTP-binding Proteins, Grouper Mx. The 2006 Annual Conference of the Fisheries Society of Taiwan, Keelung, Taiwan, Abs. # BO-16. 44. Liu Y-R, Ou M-C, Chen Y-M, Yang, H.-L., and Chen T-Y*. 2006. Relations Between Structure and RNAi Inhibition Activity of Nervous Necrosis Virus B2 Protein. The 2006 Annual Conference of the Fisheries Society of Taiwan, Keelung, Taiwan, Abs. # APN-1. 45. Chen Y-M, Su Y-L, Shie P-S, Yang, H.-L., and Chen T-Y*. 2006. Resistance to Nodavirus Activity by Coat Protein Interaction with the Interferon-regulated GTP-binding Proteins, Grouper Mx. The 2006 Annual Conference of the Fisheries Society of Taiwan, Keelung, Taiwan, Abs. # BP-6. 46. Tasi T-J, Ou M-C, Chen Y-M, Lee G-B, Lee S-S, Yang, H.-L., and Chen T-Y*. 2006. Fast Detection Method Using NNV RNA1 as Target by Microfluidic Chip. The 2006 Annual Conference of the Fisheries Society of Taiwan, Keelung, Taiwan, Abs. # BPN-14. 47. Yu-Chin Su, Yang, H.-L., Jiann-Ruey Hong*. 2006. RGNNV B2 as a novel death gene induces grouper liver cell death. 2006 The 21th Joint Annual Conference of Biomedical Sciences March 18-19; O058, p. 74. 48. Chien-Li Chiu, Jen-Leih Wu, Yang, H.-L. and Jiann-Ruey Hong*. 2006. IPNV VP3 as a novel viral death gene, targeting to ER and induces apoptosis through caspase activation in a zebrafish cell line. 2006 The 21th Joint Annual Conference of Biomedical Sciences, March 18-19; O063, p. 76. 49. Po-Chun Chen, Jen-Leih Wu, Yang, H.-L. and Jiann-Ruey Hong*. 2006. Src tyrosine kinase may mediate in IPNV-induced apoptosis cell death. 2006 The 21th Joint Annual Conference of Biomedical Sciences, March 18-19; P674, p. 276. 50. Speaker：S. P. Chen, Yang, H.-L., J. L. Wu and J. R. Hong. 2006. NOV 28-DEC 1. Betanodavirus induces mitochondria-mediated cell death in grouper cells.VNN 2006-First international symposium on viral nervous of fish. PP6. Hiroshima, Japan. 51. Y. C. Su, Yang, H.-L., J. L. Wu and J. R. Hong. 2006. Cloning and characterization of a non-structural protein B2 as a death inducer from betanodavirus. VNN 2006-First international symposium on viral nervous of fish. PP6. Hiroshima, Japan. 52. Yang, H.-L., H.Y. Lin and C.C. Lin. 2006. Nov 28. The development of an oral NNV vaccine and its efficacy evaluation in the larvae of Epinephelus coioides. 1st International symposium on viral nervous necrosis of fish, Hiroshima, Japan. 53. H.Y Lin, Y.M Chen, M.S. Chen, C.C. Lin and Yang, H.-L.. 2006. Nov 28. Mornitoring nervous necrosis virus infection in a commercil grouper hatchery in Taiwan. 1st International symposium on viral nervous necrosis of fish, Hiroshima, Japan. 54. C.C. Lin, M.S. Chen, H.Y. Lin and Yang, H.-L.. 2006. Nov 28. Establishment of experimental challenge model of grouper (Epinephelus coioides) for NNV. 1st International symposium on viral nervous necrosis of fish, Hiroshima, Japan. 55. Chen Y-M, Su Y-L, Shie P-S, Yang, H.-L., and Chen T-Y*. 2007. The Role of Grouper Mx Confers Resistance to Nodavirus. Fifteenth Symposium on Recent Advances in Cellular and Molecular Biology. Kenting, Taiwan, Abs. #P107. 56. Yang, H.-L., Chen T-Y*, and Liu Y-R. 2007. Production and Characterization of a Peptide-Based DNA Delivery System. The 22th Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan, Abs. #P539. 57. Chen Y-M, Yang, H.-L., and Chen T-Y*. 2007. Identification of Responsive Proteins for Nervous Necrosis Virus Infection by Proteomic Approach. The Seventh International Symposium on Fish Immunology. Stirling, Scotland, Abs. #P38. 58. Invite speaker: The development of an oral NNV vaccine and its application in commercial hatchery, The 3rd Malaysia international Agro-Bio Business Conference, 12-13 , 2007 Kuala Lumpur, Malaysia 59. Session leader: The agriculture and aquaculture biotechnology and opportunity, The 3rd Malaysia international Agro-Bio Business Conference, 12-13 , 2007 Kuala Lumpur, Malaysia 60. Invited speaker: The control of NNV infection by an oral vaccine, Asian-Pacific Aquaculture 2007 Conference, Hanoi, Aug.6-9, 2007 61.Invite speaker: The development of an oral NNV vaccine and its application in commercial hatchery, The 3rd Malaysia international Agro-Bio Business Conference, 12-13, 2007 Kuala Lumpur, Malaysia 62. Session leader: The agriculture and aquaculture biotechnology and opportunity, The 3rd Malaysia international Agro-Bio Business Conference, 12-13 , 2007 Kuala Lumpur, Malaysia 63. Invited speaker: The control of NNV infection by an oral vaccine, Asian-Pacific Aquaculture 2007 Conference, Hanoi, Aug.6-9, 2007 64. Chen Y-M, Yang, H.-L., and Chen T-Y*. 2007. Identification of Responsive Proteins for Nervous Necrosis Virus Infection by Proteomic Approach. The Seventh International Symposium on Fish Immunology. Stirling, Scotland, Abs. #P38. 65.Lin H.-Y., Chen Y.-M. , Wu P.-F., Chen J.-Y., and Yang H.-L. 2008. Development a gene-deleted subunit vaccine of Aeromonas hydrophila. WAS 2008, Busan, Korea. b.國內會議 1. Invited speaker 。2001。 水產動物疾病防治生物技術，臺灣水產學會年會Nov. 24, 2001 2. 許維儀，王俊傑，林翰佑，陳宗嶽，楊惠郎，以海鱺rag-1及 Ig基因之表現探討其免疫機制之發育, 九十一年度水產學會年會 3. 許維儀，王俊傑，林翰佑，陳宗嶽，楊惠郎，海鱺重要免疫基因rag-1及 Ig部份基因之選殖及序列比對, 九十一年度水產學會年會 4. 周宜黎、吳金洌、楊惠郎、洪健睿。2004 。傳染性胰臟壞死病毒凋亡基因VP3藉由活化caspase-8 和-3 使細胞凋亡。中華民國微生物學會九十三年度學術論文發表會摘要。第16頁。 5. 洪健睿、官柏志、楊惠郎、吳金洌。2004 。胰臟壞死病毒感染能活化轉錄因子NF-kB去促使細胞凋亡和降低病毒蛋白表現之双功能角色。臺灣水產學會九十三年度學術論文發表會摘要。第3頁。 6. 蘇郁清、楊惠郎、吳金洌、洪健睿。2004 。神經壞死病毒非結構性蛋白基因B2可誘發石斑魚肝臟細胞株凋亡及可被小片段干擾性RNA減緩其功能。臺灣水產學會九十三年度學術論文發表會摘要。第10頁。 7. 曹鳳儒，林翰佑，楊惠郎. 2006. Dec 16. 點帶石斑魚幾丁質脢純化，功能性分析及基因選殖. 台灣水產年會學術論文發表會. 基隆，台灣。 8. 吳佩芬，林翰佑，楊惠郎. 2006. Dec 16. Aeromonas hydrophia 的Aerolysin毒素之毒性分析. 台灣水產年會學術論文發表會. 基隆，台灣。 9.陳俐伽、蘇郁清、楊惠郎、吳金洌、洪健睿。2006. 證實神經壞死病毒B1為新表現之基因及其細胞內分佈之研究。2006台灣水產學會。BO-25; pp24。 10.Chen Y-M, Su Y-L, Shie P-S, Yang, H.-L., and Chen T-Y*. 2007. The Role of Grouper Mx Confers Resistance to Nodavirus. Fifteenth Symposium on Recent Advances in Cellular and Molecular Biology. Kenting, Taiwan, Abs. #P107. 11. Yang, H.-L., Chen T-Y*, and Liu Y-R. 2007. Production and Characterization of a Peptide-Based DNA Delivery System. The 22th Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan, Abs. #P539. 12. Chen Y-M, Shie H-P, Yang H-L, and Chen T-Y*. 2007. Identification of Responsive Proteins for Nervous Necrosis Virus Infection by Proteomic Approach. Taiwan Proteomics Society International Conference 2007. Tainan, Taiwan, Abs. #P83. 13. Chen Y-M, Shie H-P, Yang H-L, and Chen T-Y*. 2007. Proteome analysis of viral nervous necrosis grouper by two-dimensional electrophoresis. The 2007 Annual Conference of the Fisheries Society of Taiwan, Kaohsiung, Taiwan, Abs. # BO-2-2. 14. Chen Y-M, Shie P-S, Yang H-L, and Chen T-Y*. 2008. Roles of grouper Mx in regulation of cell cycle and resistance to nodavirus. The 7th Symposium on Diseases in Asian Aquaculture. Taipei, Taiwan, Abs. CP#35. 15. Chen Y-M, Shie H-P, Yang H-L, and Chen T-Y*. 2008. Identification of small heat shock protein as stress-induced molecular chaperone-like activity in nodavirus infected grouper. The 7th Symposium on Diseases in Asian Aquaculture. Taipei, Taiwan, Abs. PB#159. 16. Tasi T-J, Lee S-S, Chen Y-M, Lee G-B, Yang H-L, and Chen T-Y*. 2008. One step multiplex diagnosis for grouper pathogens detection. The 7th Symposium on Diseases in Asian Aquaculture. Taipei, Taiwan, Abs. PB#98. 17. Chen L-J, Su Y-C, Yang, H-L. Wu J-L and Hong J-R . 2007. RGNNV B1 protein plays an anti-apoptotic function with RGNNV infection in grouper fish cells. 2007 The 22th Joint Annual Conference of Biomedical Sciences, Taiwan. P607. [優秀壁報論文獎] 18. Chen L-J, Su Y-C, Yang, H-L. Wu J-L and Hong J-R . 2007. Identification of RGNNV protein B1 as a novel anti-apoptotic death gene. Annual meeting of the fisheries society of Taiwan, AO-2-3. 19. Shih C.-H., Liu H.-C., Wu C.-L., Lin C.-C., Chen Y.-M., Lin H.-Y., and Yang H.-L. 2008. 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